The research article and its cover art provided by Dr. Mohammad Taghi Jafari, a faculty member of the Department of Chemistry at Isfahan University of Technology, together with two other researchers from the university, were published in the prestigious international journal "Analytical Chemistry".
"According to the Public Relations Office of Isfahan University of Technology, this article is the result of a collaboration between Dr. Mohammad Taghi Jafari, Dr. Hossein Farrokhpour, faculty members of the Department of Chemistry, and Mohammad Hariri, a PhD researcher in the same department. The work focuses on analytical chemistry with an emphasis on the separation of isomeric compounds.
This research addresses the separation and measurement of isomeric compounds that share similar chemical structures but exhibit different properties. The importance of this topic becomes evident when considering that certain optical isomers of a compound may behave entirely differently; for example, one isomer may serve as an anticancer drug, while another may possess toxic or even carcinogenic properties. Therefore, precise separation and identification of these compounds is of great significance in pharmaceutical sciences and analytical chemistry.
According to the report, in this study, various isomers of nitroaromatic compounds were separated using an ion mobility spectrometer (IMS) equipped with a corona discharge ionization source, and the behavior of their molecular ions in the gas phase was examined.
By modifying the chemical structure of these compounds through their interactions with different alcohols, the researchers enabled the separation of the corresponding isomers. This method also allows for the separate and accurate quantification of these isomeric compounds in real samples.
The researchers emphasized that these findings pave the way for a deeper understanding of ion–modifier interactions in the drift region of IMS and can play an effective role in developing more precise measurement methods for complex environmental, pharmaceutical, and industrial samples.
It is worth noting that the ion mobility spectrometer used in this research had previously been designed and built by the same research group in the laboratory of the Department of Chemistry at Isfahan University of Technology"